Jump to content

ACE Inhibitor / Diazepam interaction.


[sh...]

Recommended Posts

I had hypertensive urgency October 2012 for which I was put on 20mg Lisinopril. Initially, the drug seemed to help somewhat with my protracted w/d syndrome -It turns out that ACE Inhibitors (lisinopril being one,) are cross-tolerant with diazepam- Then the side-effects started, and I have been unable to do any further tapering of the benzo. The doctor has ordered 30-day cardiac event monitoring to see if the arrhythmias are dangerous. This one test costs ~$1200 of my deductible. Blood work to check for renal impairment is also needed.

I am wondering if someone else on the forum withdrew or switched from a similar high a dose of this or another ACE inhibitor with success. If so, please can they share any info on which BP drug is least likely to interfere with W/D, and if a lower dose of lisinopril will help stave off some of the side-effect severity.

I do not have essential hypertension, but have a very strong vasovagal response, which makes benzo W/D difficult without the help of a blood-pressure drug.

Any thoughts on the usefulness of cardio-beeper test is also appreciated. And many thanks to the members who have already posted their lisinopril experience; It is so important to be validated in your own.

References:

http://www.google.com/patents/US4931430

http://www.ncbi.nlm.nih.gov/pubmed/2112256

 

Link to comment
Share on other sites

I had hypertensive urgency October 2012 for which I was put on 20mg Lisinopril. Initially, the drug seemed to help somewhat with my protracted w/d syndrome -It turns out that ACE Inhibitors (lisinopril being one,) are cross-tolerant with diazepam- Then the side-effects started, and I have been unable to do any further tapering of the benzo. The doctor has ordered 30-day cardiac event monitoring to see if the arrhythmias are dangerous. This one test costs ~$1200 of my deductible. Blood work to check for renal impairment is also needed.

I am wondering if someone else on the forum withdrew or switched from a similar high a dose of this or another ACE inhibitor with success. If so, please can they share any info on which BP drug is least likely to interfere with W/D, and if a lower dose of lisinopril will help stave off some of the side-effect severity.

I do not have essential hypertension, but have a very strong vasovagal response, which makes benzo W/D difficult without the help of a blood-pressure drug.

Any thoughts on the usefulness of cardio-beeper test is also appreciated. And many thanks to the members who have already posted their lisinopril experience; It is so important to be validated in your own.

References:

http://www.google.com/patents/US4931430

http://www.ncbi.nlm.nih.gov/pubmed/2112256

 

I added some commentary to a thread I started (quite some time ago) regarding Lisinopril.

 

http://www.benzobuddies.org/forum/index.php?topic=39051.msg1003318#msg1003318

 

Remember - get professional guidance for what you intend to do.

 

Link to comment
Share on other sites

 

      Reading your entry about Ace Inhibiter and Diazepam interaction.

        I take 20 mg of Linsinopril for HBP, I am also tapering Xanax via dry method. I really struggle with

        sx w/d even @ tapering .0625mg of X every 14-21 days.

        Could this be  correlation also?

         

            Notforme  :angel:

Link to comment
Share on other sites

×
×
  • Create New...