Author Topic: Are Xanax and klonopin equal in dosage?  (Read 1596 times)

[Buddie]

Are Xanax and klonopin equal in dosage?
« on: June 30, 2012, 03:06:18 am »
BB,

I am reading on different sites here and there and also from the pharmacist that .25 mgs of klonopin = .5 mgs of Xanax.

But many other equivalency charts (including Ashton) and my doctor show the dosages to be equal; .5 mgs klonopin = .5 mgs Xanax.

So I would appreciate the consensus of BB. What do you all think? Any replies very welcome. Thank you.

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[Buddie]

Re: Are Xanax and klonopin equal in dosage?
« Reply #1 on: July 03, 2012, 02:35:11 am »
Equivalencies vary person to person and also depend on what you're considering 'equal'. Xanax has a much shorter half-life than Klonopin does, so it will accumulate to a much smaller degree given the same dose taken daily for a period of weeks.

Ashton's work indicates that someone on 4mg of Xanax a day should crossover to the same dose of Valium as someone on 4mg of Klonopin a day. That's what her equivalencies are based on. It may be that if you're taking a single dose to treat an acute condition, the numbers would change. Likewise, if you're considering long term use of one vs the other, the numbers may change in the other direction. It may also be that Klonopin is more sedating, so if the primary reason the drug was being taken was to create sleepiness, then a smaller relative dose of Klonopin would be appropriate relative to Xanax.

This is a fairly complicated issue, and because one of the variables is individual metabolism, there is no right or wrong answer. I think it's fair to say that "1mg of Xanax is the equivalent of 0.5mg to 2mg of Klonopin", because depending on the context it's possible to defend any combination of the math.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Are Xanax and klonopin equal in dosage?
« Reply #2 on: July 03, 2012, 03:28:17 am »
[...],

Thank you for your reply. I've read that klonopin is somewhat singled out (as per British NHS) as variable in it's equivalencies to other benzos. This is also true with the American Psychiatric association.

The comparison I am seeing is .5 mgs Xanax = .25 mgs -.5 mgs klonopin. I tend to think it does depend on ones individual metabolism as you say and what purpose one is using it for. Complicated as you say.

[...]
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Are Xanax and klonopin equal in dosage?
« Reply #3 on: July 03, 2012, 12:54:00 pm »
One anecdote I can offer is that I used Ashton's tables to switch from 1.5mg K to 30mg V and didn't have much trouble.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Are Xanax and klonopin equal in dosage?
« Reply #4 on: July 03, 2012, 03:13:36 pm »
[...],

In your specific case, it appears that .5 mgs equivalency to .5 mgs Xanax was used for the crossover as this is the ratio also used for the Xanax cross, I believe.

[...]
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.