The issue seems to be predominantly with Fluoroquinolone Antibiotics. Ciprofloxacin, Ofloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin and Delafloxacin, which have been shown to have agonistic effects on the A1 subunit of the GABA-A receptor sites which can lead to complications during a Benzodiazepine taper or a new wave of withdrawal symptoms after a taper has already been completed.