New to scale- few questions

[[Buddie]]

She selected 300 mL because she wanted a 300 day taper (common). 
But if you want a shorter taper, just match the mL to the number of days.  For example, if you wanted a 200 day taper, start with 200 mL.

NO, the math is more complicated.  If you drop 0.5mg into 300 mL of water and remove 1 mL and drink the rest, you will have reduced only 0.0017 mg for that first day (each mL you remove is 0.0017 mg).

Each day you removed an additional 1mL (0.0017 mg of drug) so it is a very slow and even taper.

[[Buddie]]

Okay the 300 is the amount of days, right?

Any chance you could help me sort a formula out? I understand if you cannot.

[[Buddie]]

Yes, 300 days is a nice slow taper.

I will be happy to help you sort out a formula.

Right now, you are at .465 mg of your drug, correct?

If so, you can continue with that taper and switch to the water method as follows:

Each night, put 0.5 mg tablet into 300 mL of water.

Then, to get to 0.465 mg, remove 21 mL of water.

Now your mixture has exactly 0.465 mg of drug.

Do this each night but then to taper, each night remove an additional 1 mL before drinking it.

Does that help?

[[Buddie]]

Fyi …

The ODT/water mixture being discussed is a suspension.

Consequently, it will be important to (1) shake the mixture well before using it and (2) measure the reduction amount quickly before the suspended drug molecules and particles of excipient fall out of suspension.

[[Buddie]]

To add to [...] comments, after you drink the mixture, you should swirl water into the jar and drink it too.  I think that is discussed in the video.

[[Buddie]]

The more great information you give the most questions I have!

Could I chunk out my liquid taper. Say give it a try based on 30 days, 60, etc. ? If it's going well, continue, if not stop? 300 days seems like A LOT.

Tap/ well water is okay? Shaking this up evenly spreads the medication?

To get to 0.465 mg, remove 21 mL of water.- How did you calculate this math?

You said remove 1ml after I'm on .0465 ... How would I then calculate the dose I'm on?

I will have trouble with the math, but I think it's making sense to me.

Thank you- will note to shake well and drink right away then swirl and drink again.

Has anyone created an excel sheet for this?!

[[Buddie]]

.0017 = 1ml
.0034= 2ml
.0085= 5ml
.017= 10ml

Am I on the right track? Is that only accurate for a 300 day?

[[Buddie]]

so by cutting 1ml each day, you have cut by 14mls at the end of two weeks....

Is this correct

Day 1 . 50
Day 14 .4762

 (.0238 taken away over 14 days).... this is still approx a 6% cut so what is the advantage from my 6% pill cuts?

I THINK I actually might be starting to understand.

[[Buddie]]

Yes, you are doing things correctly.  Yes, this is only good when you put 0.5 mg into 300 mL of water.

Here are the answers to your other questions.

Here is the math to prove you need to remove 21 mL out of 300mL to make 0.5 mg into 0.465mg.

300mL minus (300mL times 0.465 mg divided by.5mg) = 21 mL 

If you want to calculate how much dose you are on at any time during the taper, use this equation:

dose = (how much of the mixture you are about to drink) times 0.5/300

Any water is fine.

You could try any about of days you want.  You just need to pick a plan and try it.  Journal each day your symptoms and dose and then read your journal to help make decisions about changing anything. I suggest you start with the 300 mL method to be safe.

[[Buddie]]

Why didn't you do the liquid taper?

What is the recommended ML to deduct daily?