Help with diazepam liquid solution

[[Buddie]]

Thanks for adding that info [...] it is very important as you said to trial the liquid. I’m glad I did because I didn’t adjust very well to it-made me nauseas and was getting burning in my face. I only gave it a week but like u said before 2 weeks is probably a better trial. I think you said also (pls correct me if I’m wrong) other bbs had to do a slight updose since the liquid sometimes is not as strong as the tablets
[...]

I believe you may be confusing me with another member, [...] — quite easy to do on a forum with as many members as this one.

Assuming the manufacturer follows Good Manufacturing Practices for both production and quality control, the strength (potency) of the oral solution should be the same as that of regular tablets (e.g., 1mL of the liquid will contain 1mg of drug, just as a 1mg tablet contains 1mg of drug). However, the pharmacokinetics, metabolism, and bioavailability of the liquid may indeed be slightly different compared to the solid dosage form.

Although some members do routinely recommend an updose when switching from tablets to liquid, my personal preference is to conduct a ‘mini-experiment’ to determine if one is needed.

gotcha [...] thanks for the correction

[[Buddie]]

[...],

Gotcha, thanks for the clarifications!

I am dosing three times a day right now: 1mg, 1mg, 1.5mg

My plan is to taper that .5mg from the third dose, and then ... come up with my next plan!

I really just started this and my last and first cut was .5mg at once and it was too much. About a week later, it hit me very hard. That said, it settled down after 3 weeks. So what I'm hoping to do is another similar cut but with a daily taper so as to not get the impact all at once.

I'm willing to slow down at any point - I just felt like I needed to start with a number somewhere and I'd like to see if I can knock this .5mg off in w/in a month and 25 seemed a nice round number to get the .02 decrease each day.

I'm already dealing with some nausea so really hoping I won't have the same reaction as [...] but we will see. I'm hoping that by only using liquid for a fraction of the dosing, it will help with the adjustment.

I definitely do not want to updose, so if sxs get worse, I will just go back to pills rather than updose to tolerate the liquid.

Hope that makes sense and thank you for checking my math 

[[Buddie]]

[...],

Gotcha, thanks for the clarifications!

I am dosing three times a day right now: 1mg, 1mg, 1.5mg

My plan is to taper that .5mg from the third dose, and then ... come up with my next plan!

I really just started this and my last and first cut was .5mg at once and it was too much. About a week later, it hit me very hard. That said, it settled down after 3 weeks. So what I'm hoping to do is another similar cut but with a daily taper so as to not get the impact all at once.

I'm willing to slow down at any point - I just felt like I needed to start with a number somewhere and I'd like to see if I can knock this .5mg off in w/in a month and 25 seemed a nice round number to get the .02 decrease each day.

I'm already dealing with some nausea so really hoping I won't have the same reaction as [...] but we will see. I'm hoping that by only using liquid for a fraction of the dosing, it will help with the adjustment.

I definitely do not want to updose, so if sxs get worse, I will just go back to pills rather than updose to tolerate the liquid.

Hope that makes sense and thank you for checking my math 

Hey OR, when I tried liquid I only did one of my doses,

[[Buddie]]

Two final thoughts, [...].

Generally speaking, it is easier to speed up a taper that is going well than it is to slow down and recover from a ‘too much/too fast’ taper.  Given your drug history and relatively low total daily dose, if I were in your shoes, I would give serious consideration to beginning with a more conservative taper rate than 14.29% in 25 days.  However, this is your taper so it’s totally your call as to how to proceed.

I’ve read that some members find the taste of the oral diazepam solution to be less than pleasant.  To address this, you might consider measuring your dose and then adding it to water before drinking the drug/water mixture.  Diluting the diazepam solution this way might also be less upsetting to your stomach.  (If you do decide to try this, I suggest you rinse the drinking container with water then drink the rinse water to ensure all of the original drug/water mixture has been cleared out of the container and ingested.)

Sending all best wishes your way for a successful taper ... [...]

[[Buddie]]

Thanks, [...]! Appreciate all the guidance!