Author Topic: Dry Powder Titration technique for use with small doses  (Read 5114 times)

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #20 on: November 30, 2021, 03:19:33 am »
Thanks very much [...] for helping [...] with the math. You are much better than I am explaining the math as is Slow and Steady. I really enjoy reading your progress posts.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #21 on: November 30, 2021, 04:11:03 pm »
I appreciate the kind words.  Thanks.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #22 on: February 06, 2022, 04:42:10 pm »
Hi [...]
Thank you so much for your continued help with the dry taper in low doses. My taper has been ok and my plan is to finish out the last 25%  portion of it this way. I would love if you could check my math. This is a reduction of 3% for every 2 week drop. i used your equation weight= dose*.4/.15. Could you review for me. I also wanted to ask if i wanted to use half the filler, would the equation be:
weight=dose*.2/.15?

So Grateful for this board...

dose in mg         weight in g
0.13              0.346
0.124      0.329
0.117      0.312
0.111      0.297
0.106      0.282
0.101      0.268
0.096      0.254
0.091      0.242
0.086      0.230
0.082      0.218
0.078      0.207
0.074      0.197
0.070      0.187
0.067      0.178

Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #23 on: February 06, 2022, 05:17:13 pm »
[...]:

If you are doing this following:
     -Crush 24 pills (each one is 0.5mg dose)
     -Mix with 30.8 grams of microcrystalline cellulose
Then yes, your table is perfect.

If you want to use half the filler, you equation is close but the exact equation would be:
weight = dose*(0.2075/0.15)

I am happy to hear of your progress.  Remember, you will have bad times and good times (symptoms).  When the bad happens, just let it pass and wait for the good again.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #24 on: February 06, 2022, 05:37:11 pm »
Thanks Bob so much, I so appreciate your help.  I was just curious about the equation for half the filler. Why is it not just half the original filler? Also, what is the best way to weigh out 30.8 g of filler on my Gem 20 scale? I am not sure the little pan that comes with it, is the best option. What would be your suggestion?

Hope you are doing well...

Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #25 on: February 06, 2022, 06:43:41 pm »
It is complicated but you must take into account the weight of the benzo on the numerator of the equation.

You can use most anything to weigh the powder - just make sure to tare it after you place the bowl on the scale.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #26 on: February 23, 2022, 06:01:47 pm »
Hello, [...].

Thank you for sharing your approach to tapering. Iím glad itís working for you.

Re:your request for feedback on your approach ...

Given that it involves storing powder made from crushed drug tablets for a long period of time, I thought you might find the interaction below of interest.

Hello all,

Does anyone know that if we had the drug crushed into powder and stored couple of months for later use, would involve the risk of that powder to lose it's potency, as it's not a solid pill anymore ? And basically get more WD from this as you get less absorbed in your body.

I have some big issues recently with the Clonazepam I am taking and trying to find if this is possible or not.

Yes, itís possible the properties of the active pharmaceutical ingredient in the ground up tablets might change over time depending on storage conditions (e.g. exposure to light, air, heat, and moisture can cause drug degradation).  Another possibility is the powder may absorb moisture from the air over time.  Consequently, a given weight of powder would no longer contain the same amount of drug.
« Last Edit: February 23, 2022, 06:09:58 pm by [Buddie] »
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Dry Powder Titration technique for use with small doses
« Reply #27 on: March 05, 2022, 11:02:46 pm »
Hi cerca trova,

That is a good point regarding making sure your crushed powder is protected from moisture. I am using a prescription bottle to store this powder and keeping it in a cool, dry place out of sunlight. I believe the prescription bottle I am using does have a good nearly airtight seal. You could as an additional precaution store this bottle in a high quality zip lock bag for another layer of protection. Or you could store the prescription bottle in a larger glass bottle with a tight lid to make sure that it did not absorb moisture.

Thanks for your comments and best of luck to you on your journey !


Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.