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Are there studies showing that AMPA/Glutamate Kindling/Sensitisation Reverses?


[Da...]

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I've heard multiple times that whilst GABAa receptors may be permanently damaged, glutamate receptors that have been sensitized/kindled eventually heal after 5 - 8 years. I've heard that in alcoholics kindling starts reversing after 5 years on various forums like reddit. I've also heard that

 

"After 6-8 years you are finally done, your glutamate receptors are fully healed and life goes on.

Kindling of ionotropic glutamate receptors only happens to a small percentage of those who become dependent on glutamate modulating meds or drugs, so don't worry."

 

Could someone please provide studies for this? I've been searching and can't find anything.

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[cb...]
Well, I don't know about studies but you have people here that recovered from benzos and started drinking alcohol normally without ill effects.
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