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Clonazepam+Nitrazepam help with mixing Pills into a Propylene Glycol Solution?


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Right now I'm extremely sleep deprived sorry if some of this makes no sense. If there is any information that I have not provided let me know what else I should add. I'm currently using 3.5MG Rivotril Clonazepam Roche Brand Name daily plus 10MG Nitrazepam Mogadon Brand Name. I have Roche 2MG Pills and the 0.5MG Rivotril Roche Pills that I have tried cutting in half and even cutting the 0.5MG Pills into four separate pieces, then reducing the Dose by like roughly what should be 0.125MG. .

 

I came across a Post by User: Gudruna that says "I have read from a reliable source that shaving tablets is not really as accurate as we may think due to the medication not being evenly distributed throughout each tablet. Unless the tablet is scored, 1/2 a tablet would not necessarily mean there is 1/2 the medication in each half, then when 1/2 is quartered the accuracy is even less."

 

 

Now when it comes to dissolving the Pills in Propylene Glycol I am assuming all the Binders and Fillers won't absorb and will float around. I have read that basically any Benzodiazepine can absorb in Propylene Glycol up to 4MG per each 1ML of the Solution. Some people have been able to get 10MG but it seems that requires a lot of heat and shaking/stirring. What I have read about making Benzo PG Solutions is all about using Pure Powders and I have no idea how to go about doing it with Pills that have a WAY more Fillers and Binders compared to the tiny amount of actual Clonazepam in each Pill or Nitrazepam etc.

 

I'm also assuming different Brands and different Generics of Clonazepam or Nitrazepam and Diazepam I can get my Dr. to switch Me to it but I am worried that if I tell him I want to wean down he will do it way to rapidly or simply won't be willing to help me do as slowly as possible.

 

The reason I'm worried is that you're only allowed to be Prescribed two different Benzodiazepines at once which would mean I'd need to switch from at least one or both the Clonazepam and Nitrazepam to Diazepam. Which from everything I have read you need to do it that slowly and even then it's brutally rough and it's best if possible that is to simply wean down from your current Benzo and since these 2 both are long-acting and very similar in chemical structure with basically the same half-lives.

 

I hope I didn't just type out way much and that nobody is going to read this or understand this like I said let me know if I need to add more information or some. The point of this post is how do I go about making Propylene Glycol Prescribed Pill Solutions which I got Food Grade 99.9% Pure PG. If you could please help Me Benzobuddies Community it will give me hope I might actually one day be free of these flippin devil Pills you got no idea what that would mean for me cause at this point I feel like it's hopeless and I will never ever be able to stop.

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I hope I didn't just type out way much and that nobody is going to read this or understand this like I said let me know if I need to add more information or some. The point of this post is how do I go about making Propylene Glycol Prescribed Pill Solutions which I got Food Grade 99.9% Pure PG. If you could please help Me Benzobuddies Community it will give me hope I might actually one day be free of these flippin devil Pills you got no idea what that would mean for me cause at this point I feel like it's hopeless and I will never ever be able to stop.

 

 

I have never used PG but I have read from reliable sources that 2ml of PG per mg of benzo is the proportion to use to make a viable solution.

I would suggest for you to continue cutting your tablets on the score line(if they have one) and reduce using a combination of tablets and the liquid PG solution when able. Also regarding the medication not being distributed evenly through out the tablets, while this is true, if you use a cut  tablet within the same day it should not matter especially with the longer acting benzos. The shorting acting benzo is where one may experience issues. The speed in which one metabolizes benzo, the amount of benzo one is taking along with other variables plays a huge factor in whether or not one will experience interdose issues. If you have been cutting your tablets and not having difficulty I would continue in this manner and not worry about it.

 

I'm currently using 3.5MG Rivotril Clonazepam Roche Brand Name daily plus 10MG Nitrazepam Mogadon Brand Name. I have Roche 2MG Pills and the 0.5MG Rivotril Roche Pills that I have tried cutting in half and even cutting the 0.5MG Pills into four separate pieces, then reducing the Dose by like roughly what should be 0.125MG. .

 

Starting with the 10mg Nitrazepam Mogadon (1ml = .10mg):

1) Put 1-10mg  tablet in a suitable container

2) Add 20ml PG and let sit until broken down

3) Add 80ml distilled water shake well

4) Remove and take dose

 

Like gardner suggests, start off by reducing the shorter acting benzo. So, if you are taking 10mg a day of the Nitrazepam Mogadon, I would suggest to start off by taking 7.5mg (3/4 of a 10mg tablet) along with 25ml of the above solution. You can then reduce 1 or 2ml perday or however much you feel comfortable with reducing. If you experience problems with interdose issues, only then would I consider tablets cut only on score line then adding more of the PG liquid. Because you are on such a large dose of benzo you probably will not have may issues. Give it a go :thumbsup: Keep us posted with your progress...

 

 

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The reason I asked about making a PG Solution is cuz I've been using 0.5MG Pills (which I'm running low) I tried at first breaking the 0.5MG Pills in half which left me with a runny nose like a faucet with anxiety and insomnia, hot and cold sweats high HR/BP, etc. etc. I upped my Dose back up to one 2MG Pill and 3 0.5MG pills but when I run I will have no choice but to go back to 4MG a day. I don't want to be on these Pills for the rest of my life.

 

I was hoping that I could a more precisely accurate dose through a Propylene Glycol Solution and still be able to wean down slowly and with my 2MG Pills since you know how the Doctors are apparently I am not weaning down as fast as I should be and he is not willing to let me go this slow and basically wants me dose ridiculously quickly and with bigger than 10% dose reductions which I can't even manage 5% roughly. 

 

 

 

 

I'm on Clonazepam which has a mean half-life of 30-40 Hours anywhere from 18 to 60 hours. Nitrazepam has an elimination half-life of 15–38 hours (mean elimination half-life 26 hours).

 

 

 

 

 

 

 

I don't understand do you mean 1ML equals 1MG or less? Won't adding water make it so the Dose won't be evenly mixed since the PG Glycol from what I read when it comes to raw PURE Powders, not Pills full of all these binders and fillers. It can absorb easily 4MG and up to 10MG or even a bit more from what I read about people doing it with Etizolam or Alprazolam and Diazepam raw PURE Powders.

 

Now with all these binders and fillers do I need to make the Pill into a crush Powdered form to be able to dissolve in the PG. I was assuming the fillers and binders just simply don't dissolve and that the active ingredient would be able to absorb in the Propylene Glycol with some heat and vigorous shaking I read are the best ways to do it. I also read that basically all Benzodiazepines can withstand a lot of heat before starting to degrade in potency.

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Again I'm very tired and have been getting very little sleep if any at all each night. Now, will water mixed into the Propylene Glycol make the Solution inaccurate due to the Benzodiazepines not being very slightly water-soluble with Midazolam being the one exception. My question is once you add the water in won't that make the solution which I've read about pure Etizolam/Diazepam Powders can absorb easily 4MG or less and with some heat up to 10MG and apparently Benzodiazepines are fine at a really high heating point before they start to degrade like it would have to be literally in extremely hot boiling water for example and just mild heat is definitely fine.

 

I got this information from places like bluelight.org etc. etc. I've been doing a lot of reading and would be Posting to help other people but I'm too exhausted all the time right now and focused on my own problems right now which when you word it like that sounds kind of selfish lol. Anyone going through Benzo taper/Withdrawal/Detox symptoms would completely understand.

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I'm on an Inhaler that is an Androgenic and causes Muscle Twitches and it says right on the medical pamphlet sheet that it will increase your chances of seizures. I am worried about how much of an increase in the chances of seizures it will be. The Androgenic effect I think might be making my symptoms a lot worse when it comes to anxiety and things like at least what I have about Inhalers for Asthma Patients etc.

 

Can u please tell Me where is the best place to Post about this specific question to get the best and most informative and helpful answers?

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  • 1 month later...
I can't lower my dose by even 2.5MG without my inhaler messing increasing my withdrawal by like x10,000 it's impossible. I'VE TRIED EVERY SOLUTION PROVIDD EVERY METHOD and asked every place I can go to for help which doesn't seem to be at all possible to get help and that I got no choice not even to stay on cursed benzos for the rest of my life and I REFUSE I REPEAT REFUSE TO GO THROUGH a cold-turkey taper from this high of a dos.e
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  • 3 months later...

With the Coronavirus Pandemic my Dr. has agreed to give Me a little more time due to the increased stress and anxiety. I've been dry cutting only and I can't do it anymore. The biggest reason why is I just can't get them cut evenly into 4 little even pieces or even just cutting it in half is difficult. I got super sweaty palms and aching legs and muscle spasms/twitches right now etc. so making this post is extremely difficult but I hope it's readable and if anything doesn't make sense please let me know I'll do my best to explain it in better detail.

 

What liquid amounts would I need to use for a Roche 2MG Clonazepam or 0.5MG Tablet solution. As I'm assuming I can't just use these instructions switching out with a clonazepam pill. I don't know if I mentioned it, I suck at Math even in a good state of mind.

 

Starting with the 10mg Nitrazepam Mogadon (1ml = .10mg):

1) Put 1-10mg  tablet in a suitable container

2) Add 20ml PG and let sit until broken down

3) Add 80ml distilled water shake well

4) Remove and take dose

 

Since I'm on a much higher Dose of Clonazepam I would like to reduce my Dose of that first as the Nitrazepam is less likely to cause inter-dose withdrawal. In personal experience (and others) it has longer duration of action and close to the same elimination half-life. Not to mention the Nitrazepam is far more hypnotic and more likely to cause more harsher withdrawal symptoms.

 

Thank you to anyone that's taken the time to read my post and everyone that's helped me so far.

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Since you've been cutting your pills have you thought about crushing your pills and weighing them to get your dose so you don't have to switch over to liquid titration?
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If I crushed them into a powder than it would just stick to the tray and would be even more of a pain in my LEGGS! Like I can't even sit without my legs hurting nevermind standing this is not working.

 

Not to mention the fact I need to lower my dose super small and even smaller as my total daily dose gets lower. I just can't lower my dose by using my scale to weigh it out without being totally inaccurate and varying each day I dose. Instead of it being the same reduction in dosage I'm taking daily. That is why I need to attempt using a Liquid Solution for Dosing accuracy. I hope that made sense?

 

I need to start using the Liquid Solution for Clonazepam. Even if I got off the 10MG Nitrazepam first. I still got 3MG of Clonazepam to get off of. When it gets down to the lower doses it would be helpful but if nobody knows how to make one here then I've hit the end of the line with the available options I can chose from???

 

I recently learned that my Inhaler is causing enlargement of my prostate as a side-effect that I'm experiencing strongly. On top of that I learned that cuz my Inhaler increases upper respiratory infections it's caused a lung infection or something that I've had for over a year and has started getting worse since like November. I can't see a lung specialist for like 1 Year from now at the earliest so I can't Vaporize any of my Weed if it wasn't for lack of weed and my inhaler causing increased HR/BP and anxiety even without lowering my dose it causes anxiety where as I would be able to lower my dose no problem if it wasn't for the inhaler which contributed to my lung infection that makes my need to use my Inhaler even greater.

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I just accidentally double dosed one of my Nitrazepam pills which has to messed all my hard work. I'm seesaw battling and getting nowhere just going in circles with the quality of my life going the toilet.

 

I got more to type but I'm to bloody exhausted and in to much pain from lack of food and sleep and general withdrawal symptoms to even type a paragraph or a properly understandable sentence.

 

Well cause I screwed up by accidentally double dosing my Nirazepam I was able to add a bit more information in my Post above as I'm not in as severely unbearable agony. I'm not holding my breathe for anything other than nothing.

 

But if someone is on these Forums that can give Me a place  to start it's better than how I'm failing to go about this situation I'm in.

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With the Coronavirus Pandemic my Dr. has agreed to give Me a little more time due to the increased stress and anxiety. I've been dry cutting only and I can't do it anymore. The biggest reason why is I just can't get them cut evenly into 4 little even pieces or even just cutting it in half is difficult. I got super sweaty palms and aching legs and muscle spasms/twitches right now etc. so making this post is extremely difficult but I hope it's readable and if anything doesn't make sense please let me know I'll do my best to explain it in better detail.

 

What liquid amounts would I need to use for a Roche 2MG Clonazepam or 0.5MG Tablet solution. As I'm assuming I can't just use these instructions switching out with a clonazepam pill. I don't know if I mentioned it, I suck at Math even in a good state of mind.

 

Starting with the 10mg Nitrazepam Mogadon (1ml = .10mg):

1) Put 1-10mg  tablet in a suitable container

2) Add 20ml PG and let sit until broken down

3) Add 80ml distilled water shake well

4) Remove and take dose

 

Since I'm on a much higher Dose of Clonazepam I would like to reduce my Dose of that first as the Nitrazepam is less likely to cause inter-dose withdrawal. In personal experience (and others) it has longer duration of action and close to the same elimination half-life. Not to mention the Nitrazepam is far more hypnotic and more likely to cause more harsher withdrawal symptoms.

 

Thank you to anyone that's taken the time to read my post and everyone that's helped me so far.

 

Hello watermelonforever. I am glad to hear that your doctor is now willing to give you more time to taper.

 

Here is the formulas for converting 2mg/.5mg tablets of clonazepam to liquid:

 

Starting with the 2mg tablet of clonazapam (1ml = .10mg):

1) Put 1-2mg  tablet in a suitable container

2) Add 4ml PG and let sit until broken down

3) Add 16ml distilled water shake well

4) Remove and take dose

 

 

.5mg of clonazapam (1ml = .10mg):

1) Put 4-.5mg  tablets in a suitable container

2) Add 4ml PG and let sit until broken down

3) Add 16ml distilled water shake well

4) Remove and take dose

 

If you need more help let us know. Wishing you the very best with your taper.

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