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Study, Jul/19: "Cessation of fluoxetine treatment increases alcohol seeking..."


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The full title of this Spanish/American study is "Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala".

 

This is a rat study, so that needs to be kept in mind when considering the results. Whether or not the results of such a study can be extrapolated to humans is unknown. However, the topic may be of interest to people around here -- especially because alcohol and benzodiazepines have effects on the GABAA receptors. I, for one, wonder whether getting off fluoxetine (AKA Prozac) might have similar effects in the brains of those dealing with benzodiazpine withdrawal.

 

I'm putting links to both the abstract and full study here, in case anyone wants to have a look.

 

Abstract:

 

https://www.ncbi.nlm.nih.gov/pubmed/31339221

 

Full Study:

 

http://sci-hub.tw/https://www.ncbi.nlm.nih.gov/pubmed/31339221 

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Interesting study. Personally, I would prefer to read some research utilizing phytocannabinoids i.e. "pot" rather than prozac in regard to various kinds of withdrawals but, thanks for reporting on this.
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