DLMT question

Is mortar and pestle needed or can I Just dissolve Tablet in liquid?

 

Thanks

 

Is mortar and pestle needed or can I Just dissolve Tablet in liquid?

 

Thanks

Most tablets dissolve very readily.  So mfgrs do use a coating that retards moisture, and my require crushing.

 

If your tablet deconstructs/disintegrates in the liquid, then no crushing is needed.  NOTE:  There will always be some insoluble excipients remaining.  Don't worry about them, they don't matter.

Thanks.

 

Should I dissolve the tablet into the Water First

or into PG/Vodka or after I've

Mixed Water with PG/vodka?

 

Does it Play any role?

Dissolve in the solvent, then dilute with water.

Thank you.

Put 27,4mg Tablet in 54,8 PG but Tablet doesn't dissolve.

What to do?

Thanks

 

Ingredients per Tablet:

 

Active substance Flurazepam 27,4mg

Lactose-1-water + auxiliary material

Cellulose powder excipient +

Hyprolose excipient, low-substituted +

Auxiliary material silicon dioxide, highly disperse +

Auxiliary material corn starch +

Magnesium auxiliary stearate +

Auxiliary Glycerol dibehenat +

 

Thank you.

Put 27,4mg Tablet in 54,8 PG but Tablet doesn't dissolve.

What to do?

Thanks

 

Ingredients per Tablet:

 

Active substance Flurazepam 27,4mg

Lactose-1-water + auxiliary material

Cellulose powder excipient +

Hyprolose excipient, low-substituted +

Auxiliary material silicon dioxide, highly disperse +

Auxiliary material corn starch +

Magnesium auxiliary stearate +

Auxiliary Glycerol dibehenat +

 

Should I so substitution & then DLMT?

 

Thanks

You can crush ir before you add it to the solvent. or muddle it when its in the solvent. 

 

Anything that breaks up the tablet so the active ingredient can dissolve will work.