Help needed about how to transition from a pipette, to syringes.

Hello everyone,

I have been tapering Lorazepam, and are using the daily microtaper.

I measure my doses with a micropipette.

Can anyone here help me to transition from the pipette, to syringes please?

My daily dose is at 1.194mgs. I taper .001mgs per day, in 4 doses.

Thank you, wishing you all healing blessings 

What concentration is your solution?

The easiest way to transition from a micropipette to syringes is to make your solution more dilute.

Thank you for your response dear Hope.

I dilute 22 0.5mg tablets, in 11ml of Vodka.

I then draw 4 doses for the day, using the pipette.

My thought is to use a syringe instead of the pipette.

But I am uncertain as to how to work the pipette, to translate to a syringe.

Or the other way around.

Wishing you healing blessings 

You dissolve 22 tablets??? Is that a typo?

That is a 1 mg/mL solution, assuming all the lorazepam dissolves. Do you then use the micro pipette to draw up 0.2985 mL for each dose?

You could dissolve 20 tablets in 20 mL vodka (recommended is 2 mL vodka for every mg drug). Then add 80 mL water. Now you have a solution that is 0.1 mg/mL. Your daily dose (1.194 mg) is 11.94mL, which you then divide into 4 doses. Each 0.001mg reduction is 0.01 mL. Which can be kind of hard to measure with a syringe, even a 1 mL syringe

I am not so careful with my quarter doses. I put my whole daily dose (which I measure out carefully) into one bottle and swig about a quarter of it when I dose.

 

 

Thank you for your response dear Hope.

I dilute 22 0.5mg tablets, in 11ml of Vodka.

I then draw 4 doses for the day, using the pipette.

My thought is to use a syringe instead of the pipette.

But I am uncertain as to how to work the pipette, to translate to a syringe.

Or the other way around.

 

Wishing you healing blessings 

To dissolve 1mg of benzo, you need 2ml of vodka.  So your 11mgs lorazpam requires 22ml vodka.

My suggestion:

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

Your 1.6mg dose would be 16ml, or divided into 4 X .4mg, would be 4 mls.  Simply draw up the appropriate amount of liquid with either a 1ml or a 10ml oral syringe.

You dissolve 22 tablets??? Is that a typo?

 

That is a 1 mg/mL solution, assuming all the lorazepam dissolves. Do you then use the micro pipette to draw up 0.2985 mL for each dose?

 

You could dissolve 20 tablets in 20 mL vodka (recommended is 2 mL vodka for every mg drug). Then add 80 mL water. Now you have a solution that is 0.1 mg/mL. Your daily dose (1.194 mg) is 11.94mL, which you then divide into 4 doses. Each 0.001mg reduction is 0.01 mL. Which can be kind of hard to measure with a syringe, even a 1 mL syringe

 

I am not so careful with my quarter doses. I put my whole daily dose (which I measure out carefully) into one bottle and swig about a quarter of it when I dose.

Hope, w0w!!

You are understanding this exactly 

Yes, I am on hold at 1.194mgs per day, because I got hit really hard, who knows why.

I have been following the same method for a long time.

And suddenly my wd symptoms are acute 

I began to worry that maybe the pipette was malfunctioning, this is why I thought to try syringes.

So when I hopefully I am able to resume the taper, I will be at 1.193mgs.

I will then draw 0.29825ml for each of the 4 doses.

I use the pipette, and deposit each draw into a small jar.

I keep these in the fridge, and take each, every 6 hours.

Each dose, I dilute in the jar with a bit of water, and drink.

The solution of 22 0.5mg tablets into 11ml vodka, I keep in the fridge and dose for 5 days,

drawing the 4 doses for each day, from it.

What do you think? Keep up going as usual, since a syringe will not help?

Thank you so much .. I am grateful that you are here  :smitten:

 

 

Thank you for your response dear Hope.

I dilute 22 0.5mg tablets, in 11ml of Vodka.

I then draw 4 doses for the day, using the pipette.

My thought is to use a syringe instead of the pipette.

But I am uncertain as to how to work the pipette, to translate to a syringe.

Or the other way around.

 

Wishing you healing blessings 

 

To dissolve 1mg of benzo, you need 2ml of vodka.  So your 11mgs lorazpam requires 22ml vodka.

 

My suggestion:

 

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

 

Your 1.6mg dose would be 16ml, or divided into 4 X .4mg, would be 4 mls.  Simply draw up the appropriate amount of liquid with either a 1ml or a 10ml oral syringe.

Thank you so much dear builder, I appreciate your response.

I am a bit confused, in that my daily dose is at 1.164mgs, and not at 1.6mgs

Sorry to give you additional work,

but I hope that you are willing to adjust the method that you are proposing.

Thank you again, for your valuable help, and interest.

Blessings 

My background is analytical chemistry. I haven't worked in a laboratory since 1995 though. So this taper I'm on kind of reminds me of working in the lab. I bought graduated cylinders and plastic syringes, glass droppers, 500 mL glass media bottles, and everything. It's kind of fun that way.

I do suggest a more dilute solution using syringes. That way, the error in volume is not so bad. By this I mean, a tiny bit off will not be such a big deal in dose. Using the micropipettes, a tiny bit off with such a concentrated solution could cause problems.

Where did you get a micropipette from? Is it electronic? Air displacement pipette? Did you buy the tips to go with it?

My background is analytical chemistry. I haven't worked in a laboratory since 1995 though. So this taper I'm on kind of reminds me of working in the lab. I bought graduated cylinders and plastic syringes, glass droppers, 500 mL glass media bottles, and everything. It's kind of fun that way.

 

I do suggest a more dilute solution using syringes. That way, the error in volume is not so bad. By this I mean, a tiny bit off will not be such a big deal in dose. Using the micropipettes, a tiny bit off with such a concentrated solution could cause problems.

 

Where did you get a micropipette from? Is it electronic? Air displacement pipette? Did you buy the tips to go with it?

Very impressive, you have my highest respect, dear Hope 

Although I have been using the pipette for some time now, I am not aware of the information that you just shared.

I purchased mine at Amazon, with the tips. It is not electronic, or an air displacement pipette.

I pretty much eye ball the adjustment, each day I need to draw the solution.

So having learned the information that you shared, I am thinking that I probably err in handling it.

I have had ongoing symptoms since the beginning of this taper,

but as I mentioned earlier, I suddenly am experiencing clusters of bothersome symptoms, that I never had before showing up as acute   So this could be the reason.

The solution you suggested earlier, I can follow, but what to do, since the thought is that the doses would be hard to measure, even with a 1mL syringe?

Thank you so much, I am deeply grateful for your effort to help me 

 

 

Thank you for your response dear Hope.

I dilute 22 0.5mg tablets, in 11ml of Vodka.

I then draw 4 doses for the day, using the pipette.

My thought is to use a syringe instead of the pipette.

But I am uncertain as to how to work the pipette, to translate to a syringe.

Or the other way around.

 

Wishing you healing blessings 

 

To dissolve 1mg of benzo, you need 2ml of vodka.  So your 11mgs lorazpam requires 22ml vodka.

 

My suggestion:

 

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

 

Your 1.6mg dose would be 16ml, or divided into 4 X .4mg, would be 4 mls.  Simply draw up the appropriate amount of liquid with either a 1ml or a 10ml oral syringe.

 

Thank you so much dear builder, I appreciate your response.

I am a bit confused, in that my daily dose is at 1.164mgs, and not at 1.6mgs

Sorry to give you additional work,

but I hope that you are willing to adjust the method that you are proposing.

 

Thank you again, for your valuable help, and interest.

 

Blessings 

Your siggy says 1.6, but follow the same prep instructions, you still have a .1mg per ml solution

1.164mg would be 11.64ml.  4 divided doses would be 2.91ml each.

Again, easy to measure with 1 and 10 ml syringes.

 

 

Thank you for your response dear Hope.

I dilute 22 0.5mg tablets, in 11ml of Vodka.

I then draw 4 doses for the day, using the pipette.

My thought is to use a syringe instead of the pipette.

But I am uncertain as to how to work the pipette, to translate to a syringe.

Or the other way around.

 

Wishing you healing blessings 

 

To dissolve 1mg of benzo, you need 2ml of vodka.  So your 11mgs lorazpam requires 22ml vodka.

 

My suggestion:

 

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

 

Your 1.6mg dose would be 16ml, or divided into 4 X .4mg, would be 4 mls.  Simply draw up the appropriate amount of liquid with either a 1ml or a 10ml oral syringe.

 

Thank you so much dear builder, I appreciate your response.

I am a bit confused, in that my daily dose is at 1.164mgs, and not at 1.6mgs

Sorry to give you additional work,

but I hope that you are willing to adjust the method that you are proposing.

 

Thank you again, for your valuable help, and interest.

 

Blessings 

 

Your siggy says 1.6, but follow the same prep instructions, you still have a .1mg per ml solution

 

1.164mg would be 11.64ml.  4 divided doses would be 2.91ml each.

 

Again, easy to measure with 1 and 10 ml syringes.

Sorry, my siggy has not been updated recently 

If you do not mind, and due to the fact that my brain is slow catching up with numbers,

would you please write out the prep instructions, for 1.164mgs per day?

It will help me to see it spelled out 

Thank you dear builder. I appreciate your help 

 

 

Sorry, my siggy has not been updated recently 

If you do not mind, and due to the fact that my brain is slow catching up with numbers,

would you please write out the prep instructions, for 1.164mgs per day?

It will help me to see it spelled out 

 

Thank you dear builder. I appreciate your help 

The prep instructions are the same:

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

Based on your current dose of 1.164. this will be a 8-10 day supply.

 

 

Sorry, my siggy has not been updated recently 

If you do not mind, and due to the fact that my brain is slow catching up with numbers,

would you please write out the prep instructions, for 1.164mgs per day?

It will help me to see it spelled out 

 

Thank you dear builder. I appreciate your help 

 

The prep instructions are the same:

 

 

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

 

Based on your current dose of 1.164. this will be a 8-10 day supply.

Builder, can you please go a step further, and tell me what to do next?

This is new to me, and I feel lost ..

If I am dropping .001mg per day, how much do I draw into the syringe, for each of the 4 doses, when I resume the taper at 1.193mgs?

What size syringe(s) should they be?

And dropping .001each day, how do I draw the lesser amount for each of the following days, past 1.193mgs?

Thank you, so much!

 

 

Sorry, my siggy has not been updated recently 

If you do not mind, and due to the fact that my brain is slow catching up with numbers,

would you please write out the prep instructions, for 1.164mgs per day?

It will help me to see it spelled out 

 

Thank you dear builder. I appreciate your help 

 

The prep instructions are the same:

 

 

Combine 10mg lorazepam + 20ml vodka + 80ml water.  That gives you 100mls dilute liquid, .1mg per ml.

 

Based on your current dose of 1.164. this will be a 8-10 day supply.

 

Builder, can you please go a step further, and tell me what to do next?

This is new to me, and I feel lost ..

 

If I am dropping .001mg per day, how much do I draw into the syringe, for each of the 4 doses, when I resume the taper at 1.193mgs?

 

What size syringe(s) should they be?

 

And dropping .001each day, how do I draw the lesser amount for each of the following days, past 1.193mgs?

 

Thank you, so much!

Your liquid will be .1mg per ml.  So if you want to taper .001mg/day, that's .01ml per day.  Lower your dose by .01ml each day. (To convert mgs to mls, just move the decimal one place to the right.....    .001mg=.01ml)

So starting at 1.193mg, your daily schedule would be:

11.93ml        (1.193mg)

11.92ml        (1.192mg)

11.91ml        (1.191mg)

11.90ml        (1.192mg)

etc...

The easiest way to do multiple doses is draw out the whole days dose, and just (eyeball) divide that into 4 sub doses.  Accuracy really is NOT important.  Personally, I would put the whole days dose in a measuring cup and then add enough water to bring the level up to 1 cup.  Then just take 1/4 cup each dose.

I would suggest a 1ml and 10ml oral syringe.  11.93mls for example would be 10ml fill  (10ml syringe)  + .93 (1ml syringe)  Again accuracy is not nearly as important as consistency.  Follow the same procedure each day, with the same equipment, and you'll be fine

Thank you dear builder, for all the work!

I am deeply grateful, and hope that if I stumble, I can ask again.

One more question please, what do you mean when you say " (To convert mgs to mls, just move the decimal one place to the right.....    .001mg=.01ml)

Where would the decimal be?

Wishing you abundant blessings 

 

 

Thank you dear builder, for all the work!

I am deeply grateful, and hope that if I stumble, I can ask again.

 

One more question please, what do you mean when you say " (To convert mgs to mls, just move the decimal one place to the right.....    .001mg=.01ml)

 

Where would the decimal be?

 

Wishing you abundant blessings 

Look at the digits and decimals ("periods") in the example.

.001mg=.01ml

1/thousandth  is 3 digits (001) preceded by a decimal point.  1/hundredth is 2 digits (01) preceded by a decimal point .  To convert thousandths (.001) to hundredths (.01) you moved the decimal point one place to the right.

You just move the decimal to multiply or divide by 10s.

I am still studying this builder ..

Hoping to start feeling better, and use it.

Wishing you all the best.

Anoushka