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Diazepam Withdrawal Case Reports (For Your "Doctor Education" File)


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This one, published in 1983, would be a very good one to bookmark for if/whenever we may need an "authoritative" study to convince the disbelieving docs.  ::)

 

 


CASE REPORTS

Diazepam Withdrawal

FELIX W. LEUNG, MD

PHYLLIS A. GUZE, MD

 

europepmc.org/articles/pmc1010653/pdf/westjmed00197-0100.pdf

 

Discussion

 

Diazepam withdrawal reaction was first described by Hollister and co-workers in 1963 in studies of diazepam treatment in newly admitted schizophrenic patients. We have identified 33 cases of diazepam withdrawal detailed in the English medical literature (Table 1). The single most convincing case was reported by Winokur and associates, with verification of the diagnosis by a placebo-controlled, double-blind protocol.

The exact incidence of diazepam withdrawal reactions is not known. In addition to the 33 cases noted above, several authors have reported in a general way cases of withdrawal reactions among their patients. One possible reason why such withdrawal reactions are uncommonly seen is that patients may abort these reactions early on. They may think that their original symptoms are returning and reinstitute taking the drug.

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