Jump to content

need "translation" of this Librium mumbo jumbo


[ga...]

Recommended Posts

Does anybody speak chemistry-ese and can tell me what this says about dissolving Librium in alcohol and water? (At least I think that's what this is about!)

 

Experimental solubilities of three benzodiazepines (chlordiazepoxide, diazepam, and lorazepam) in ethanol + water mixtures at 303.2 K are reported. The solubility of drugs was increased with the addition of ethanol and reached the maximum value of a volume fraction of 90 % of ethanol. The Jouyban−Acree model was used to fit the experimental data, and the solubilities were reproduced using previously trained version of the Jouyban−Acree model and the solubility data in mono solvents in which the overall mean relative deviations (OMRDs) of the models were 8.6 %, 21.9 % and 19.3 %, respectively, for the fitted model, the trained version for ethanol + water mixtures and generally trained version for various organic solvents + water mixtures.

 

I am going to be so, so sad when I finish with my intensol and have to start dissolving those L capsules. :'(

 

Actually, I take that back. I am going to be so, so happy to be done with the alprazolam intensol!!!  :clap:

Link to comment
Share on other sites

Gard,

 

Go back to the thread in the link and look at posts #37 and #46.  The L data from that article is already boiled down in those posts.

Link to comment
Share on other sites

Gard,

 

Go back to the thread in the link and look at posts #37 and #46.  The L data from that article is already boiled down in those posts.

 

OK, I think you mean the link on the MT thread that links to the other thread with the cool chart, right? 

Link to comment
Share on other sites

×
×
  • Create New...