How to get from 4 doses a day to 1

I'm getting close to jumping and wondering how everyone decides how to drop down to less doses per day? Or is is reasonable to just drop all at once if they are even? Or will this be too hard on my body. I've doses 4 times per day for most of my taper due to fast metabolism of the drug.

I'd eliminate them one at a time, which dose do you think you can afford to lose?  Do you feel you're getting any therapeutic benefit from your doses at this point?