Compounding Pharmacy Liquid Klonopin

[[Buddie]]

Hi [...],

So I just got off the phone with Roxanne West war, the distributor of the Valium solution. They said they cannot confirm if the solution mixes evenly in water or not (which kind of freaks me out when with liquid titration) Do you think it’s safer to use the pills for liquid titration?

Thanks!
mdv

It does.  The label will even say "Dilute before using..."

Using pills to make your own solution is a fully satisfactory option, but if you have access to Rx liquid, that would always be my choice (and was in fact what I used for my taper).

[[Buddie]]

Hi [...],

So I just got off the phone with Roxanne West war, the distributor of the Valium solution. They said they cannot confirm if the solution mixes evenly in water or not (which kind of freaks me out when with liquid titration) Do you think it’s safer to use the pills for liquid titration?

Thanks!
mdv

It does.  The label will even say "Dilute before using..."

Using pills to make your own solution is a fully satisfactory option, but if you have access to Rx liquid, that would always be my choice (and was in fact what I used for my taper).

mdv ... I see you’ve posted the same question on another thread ... am I correct that the prescription oral solution you are using is 5mg/5mL?  If so, the label does not say dilute before using. I just don’t want you to get confused!

[[Buddie]]

Hi [...],

So I just got off the phone with Roxanne West war, the distributor of the Valium solution. They said they cannot confirm if the solution mixes evenly in water or not (which kind of freaks me out when with liquid titration) Do you think it’s safer to use the pills for liquid titration?

Thanks!
mdv

It does.  The label will even say "Dilute before using..."

Using pills to make your own solution is a fully satisfactory option, but if you have access to Rx liquid, that would always be my choice (and was in fact what I used for my taper).

mdv ... I see you’ve posted the same question on another thread ... am I correct that the prescription oral solution you are using is 5mg/5mL? If so, the label does not say dilute before using. I just don’t want you to get confused!

Yes, the mfgr's label does.  Specifically it says "Dilute before using to enhance palatability"

This is a dilutable solution using propylene glycol as a solvent, and can be extensively diluted to water, with no change to the active ingredient, other than changing the concentration ratio.

If you open this link, you will see pics of both the West and Roxane labels with those exact words.

https://www.google.com/search?q=diazepam+oral+solution+5mg/5ml&client=firefox-b-1-d&sxsrf=ACYBGNT9KdBg8NujuZN0dgbPNfZbX2WUjQ:1570223773408&tbm=isch&source=iu&ictx=1&fir=PLhqGlu4n-WT_M%253A%252Cdv_1L11fcsutRM%252C_&vet=1&usg=AI4_-kRm9kFDKEecgyv-GkqwZ6hVsWPP2w&sa=X&ved=2ahUKEwjL_-yxw4PlAhXDc98KHTZqAZkQ9QEwAHoECAUQAw&biw=1366&bih=654#imgrc=1i6cROSdGnq1jM:&vet=1

[[Buddie]]

Hi [...],

So I just got off the phone with Roxanne West war, the distributor of the Valium solution. They said they cannot confirm if the solution mixes evenly in water or not (which kind of freaks me out when with liquid titration) Do you think it’s safer to use the pills for liquid titration?

Thanks!
mdv

It does.  The label will even say "Dilute before using..."

Using pills to make your own solution is a fully satisfactory option, but if you have access to Rx liquid, that would always be my choice (and was in fact what I used for my taper).

mdv ... I see you’ve posted the same question on another thread ... am I correct that the prescription oral solution you are using is 5mg/5mL? If so, the label does not say dilute before using. I just don’t want you to get confused!

Yes, the mfgr's label does.  Specifically it says "Dilute before using to enhance palatability"

This is a dilutable solution using propylene glycol as a solvent, and can be extensively diluted to water, with no change to the active ingredient, other than changing the concentration ratio.

If you open this link, you will see pics of both the West and Roxane labels with those exact words.

https://www.google.com/search?q=diazepam+oral+solution+5mg/5ml&client=firefox-b-1-d&sxsrf=ACYBGNT9KdBg8NujuZN0dgbPNfZbX2WUjQ:1570223773408&tbm=isch&source=iu&ictx=1&fir=PLhqGlu4n-WT_M%253A%252Cdv_1L11fcsutRM%252C_&vet=1&usg=AI4_-kRm9kFDKEecgyv-GkqwZ6hVsWPP2w&sa=X&ved=2ahUKEwjL_-yxw4PlAhXDc98KHTZqAZkQ9QEwAHoECAUQAw&biw=1366&bih=654#imgrc=1i6cROSdGnq1jM:&vet=1

“Dilute before using to enhance palatability” is not the same as what you routinely recommend.  If you read the administration info in the drug pamphlets, it means “Put your entire dose in water or another liquid (or sometimes the pamphlet will suggest a soft food like applesauce) before you take it. Ingest the results immediately. Do not store.”

[[Buddie]]

[...], why do you insist in creating anxiety and uncertainty in such a simple concept. 

Solution is dilutable.  The label says so.  It does not offer any limits on the dilution ratio.  In fact, it doesn't even specify that is has to be dilutable with water.

Didn't you post somewhere you were a chemist.  This is junior high chemistry.

[[Buddie]]

“Dilute before using to enhance palatability” is not the same as what you routinely recommend.  If you read the administration info in the drug pamphlets, it means “Put your entire dose in water or another liquid (or sometimes the pamphlet will suggest a soft food like applesauce) before you take it. Ingest the results immediately. Do not store.”

I have read and researched many pages of info re: Roxane/West Labs Diazepam Oral Solution, 5ml=5mg.  (I took it for 2 years, and I never take any med without careful research)

I have never found those instructions , or any similar instruction.  In fact, other then the above referenced label instruction ("Dilute before using to enhance palatability"), I have never found any instructions for diluting this product.

The Diazepam Intensol 5mg=1ml, and the 5ml Dose Cups (labeled "For Institutional Use Only") instructions/PDLs do include some language similar to what you have paraphrased

[[Buddie]]

“Dilute before using to enhance palatability” is not the same as what you routinely recommend.  If you read the administration info in the drug pamphlets, it means “Put your entire dose in water or another liquid (or sometimes the pamphlet will suggest a soft food like applesauce) before you take it. Ingest the results immediately. Do not store.”

[...],  I appreciate your efforts as a document editor.  But in one of your old posts you yourself talk about making a solution to to taper: http://www.benzobuddies.org/forum/index.php?topic=217631.msg2796209#msg2796209  Edited to add: So I would guess you understand the purpose of creating and diluting a solution for tapering.

People dilute liquid Valium with water for several reasons.

1. Undiluted the liquid valium is very harsh tasting.  Once diluted to a 9 to one ratio of water to liquid Valium it tastes like mild cough syrup.

2. The liquid valium is quite sticky and if you take it directly a small amount might stick in the syringe.

3. Most importantly, diluting the liquid valium gives you a solution with a lower concentration of valium, which allows you taper daily by a smaller amount.
    I use a 10 ML syringe that has markings down to .2ml and a 1 ML syringe that allows me to easily make cuts of .1ml.  .1 ML of the solution is
    equivalent to .01 mg of valium, that is 1/100 of a milligram.  If the liquid valium was undiluted I could only make cuts by .2 mg.  But diluted I can
    easily make cuts   .01 mg.  This works better for a daily liquid micro taper.

[[Buddie]]

[...],  I appreciate your efforts as a document editor.  But in one of your old posts you yourself talk about making a solution to to taper: http://www.benzobuddies.org/forum/index.php?topic=217631.msg2796209#msg2796209

People dilute liquid Valium with water for several reasons.

1. Undiluted the liquid valium is very harsh tasting.  Once diluted to a 9 to one ratio of water to liquid Valium it tastes like mild cough syrup.

2. The liquid valium is quite sticky and if you take it directly a small amount might stick in the syringe.

3. Most importantly, diluting the liquid valium gives you a solution with a lower concentration of valium, which allows you taper daily by a smaller amount.
    I use a 10 ML syringe that has markings down to .2ml and a 1 ML syringe that allows me to easily make cuts of .1ml.  .1 ML of the solution is
    equivalent to .01 mg of valium, that is 1/100 of a milligram.  If the liquid valium was undiluted I could only make cuts by .2 mg.  But diluted I can
    easily make cuts   .01 mg. This works better for a daily liquid micro taper.

  :

[[Buddie]]

 

People dilute liquid Valium with water for several reasons.

1. Undiluted the liquid valium is very harsh tasting.  Once diluted to a 9 to one ratio of water to liquid Valium it tastes like mild cough syrup.

2. The liquid valium is quite sticky and if you take it directly a small amount might stick in the syringe.

3. Most importantly, diluting the liquid valium gives you a solution with a lower concentration of valium, which allows you taper daily by a smaller amount.
    I use a 10 ML syringe that has markings down to .2ml and a 1 ML syringe that allows me to easily make cuts of .1ml.  .1 ML of the solution is
    equivalent to .01 mg of valium, that is 1/100 of a milligram.  If the liquid valium was undiluted I could only make cuts by .2 mg.  But diluted I can
    easily make cuts   .01 mg.  This works better for a daily liquid micro taper.

and... while "precision" and "accuracy" really not terribly important, dilution does dramatically reduce the error factor.  With a .1mg = 1ml solution, a measurement error of .1ml is only .01 (one/one hundredth) of a milligram.

[[Buddie]]

Quite, I used a compounded liquid k during my taper. I live in U.S. Very easy to use. I am now off, since end of June. Espy