Author Topic: Where can I find instructions for liquid titration of Clonazepam?  (Read 732 times)

[Buddie]

My doctor has given me the go ahead to start a micro taper of my Clonazepam. He wants me to get off that one first and then taper the Valium as Iíve been on Clonazepam regularly for a much shorter period of time. A liquid taper seems the most accurate way to go to me, however there isnít a compounding pharmacy here capable of doing that. So Iím looking for resources with instructions for a liquid taper.

Thanks!

-Z
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #1 on: January 11, 2023, 01:06:58 am »
We donít actually have instructions since itís such an individual process but YouTube has a lot of videoís you can watch so you could start there then we can help you figure out your specific needs.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #2 on: January 11, 2023, 02:28:14 pm »
Ok great, thanks!
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #3 on: January 11, 2023, 02:34:00 pm »
Here is an example to get you started:

Milk Demo
https://youtu.be/L1DgY33JKpE
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #4 on: January 14, 2023, 10:24:14 pm »
So today I reduced from .5 to .475 of Klonopin using a gram scale, and feeling it some already. I feeling relatively stable at .5 but I figure all reductions will cause some bad feelings for awhileÖ.

Due to the inaccuracy of my scale Iíve decided to do a liquid titration. Iím a bit mathematically challenged though. Today I made a 5 percent cut, but am feeling it. I told my doctor I wanted to reduce my K dosage by 10 percent over the next 10 days, so Iím thinking of just going back up to .5 and starting the liquid titration beginning tomorrow.

If I dissolve a .5mg tablet of Clonazepam into 300ml of water , removing 3ml the first day would be a one percent cut. The next day Iíd remove 6ml , then 9ml, etc. adding one percent to each time. Am I thinking this through correctly?

I believe this will be smoother on my system and I can make my own spreadsheet, just want to make sure Iím not squandering the math here.

Thanks for yíallís support.

Peace and love,

Z
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #5 on: January 16, 2023, 03:35:32 pm »
If I dissolve a .5mg tablet of Clonazepam into 300ml of water , removing 3ml the first day would be a one percent cut. The next day Iíd remove 6ml , then 9ml, etc. adding one percent to each time. Am I thinking this through correctly?

That is correct that the first reduction would be 1%, but the next reduction would be a slightly larger percent, because you're removing the same amount but from a smaller starting dose. As you continue to cut 3 mL each time, your percentage cut will grow.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #6 on: January 16, 2023, 04:26:08 pm »
[...] has made an important point ó one of the potential Ďgotchasí of making fixed amount reductions in dose is that the percent reduction increases over time.  For example, over the first 30 days of the taper youíre considering, the amount of liquid ingested would begin at 300mL and end at 210mL.  Thatís a 30% reduction in dose.  Over the second 30 days, the amount would decrease from 210mL to 120mL ó a 42.8% reduction.

PS When you add water to a regular clonazepam tablet, the active pharmaceutical ingredient (API) and excipients in the tablet disperse (as in disintegrate, fall apart).  Because clonazepam (the API) has an extremely low solubility in water, it does not dissolve (the same applies to the water-insoluble excipients in the tablet).
« Last Edit: January 16, 2023, 04:51:25 pm by [Buddie] »
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #7 on: January 23, 2023, 11:08:52 am »
Thanks for the information. I quickly realized that the water method was not working with Klonopin- after one try I decided to just get a nail file and start making small reductions.

I recently cut from .5 K to .48 and I cut from 12V to 11.5

I was quite stable, and now it is very hard to function again due to intense symptoms. I made the mistake of making this cut before a vacation with my wife, and I am considering moving back up to the dose I was stable on so as not to ruin this trip.

But part of me feels I have to hold here and wait it out. Anyone have any thoughts? I made this cut on 1-15.
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.

[Buddie]

Re: Where can I find instructions for liquid titration of Clonazepam?
« Reply #8 on: January 26, 2023, 09:28:57 pm »
Thanks for the information. I quickly realized that the water method was not working with Klonopin- after one try I decided to just get a nail file and start making small reductions.

I recently cut from .5 K to .48 and I cut from 12V to 11.5

I was quite stable, and now it is very hard to function again due to intense symptoms. I made the mistake of making this cut before a vacation with my wife, and I am considering moving back up to the dose I was stable on so as not to ruin this trip.

But part of me feels I have to hold here and wait it out. Anyone have any thoughts? I made this cut on 1-15.

Hi!

Ive been tapering off of 1mg (0.330g) clon since 12.1.22 and am down to 0.266g starting this week. Iíve been having scale issues, which I canít seem to resolve though many kind souls have tried to help me here. Iím now wondering if liquid titration is the way to go. I have yet to find a compounding pharmacy that I can afford. ALL of it is confusing to my brain. May I ask what type of scale youíre using? I have the Smart Weigh Gem 50, but my drafty, crooked antique house could be constantly throwing things off. I only wish I was at the point where I could just file down from one pill.  I know you donít see it this way, but youíre lucky!  :D I hope the filing is working for you.

❤️
C
Suggestions, opinions and/or advice provided by the author of this post should not be regarded as medical advice; nor should it substitute for professional medical care. Consult your doctor before making any changes to your medication. Please read our Community Policy Documents board for further information.